'Another study proves that artificial sweeteners like aspartame are harmful to your health. The study, which was published in the African Journal of Traditional, Complementary and Alternative Medicines, has revealed that aspartame damages the brain. In particular, consuming this chemical sweetener for a long time will increase oxidative stress in the brain tissue and will disrupt neurotransmitters that are important in physiological functions.
Researchers from King Abdulaziz University in Saudi Arabia examined the effect of aspartame consumption on neurotransmitters and oxidative stress in the brain of rats. For the study, they observed four groups of rats. One group served as the control group, while the other three groups received aspartame at a dose of 50, 75, and 125 milligrams per kilogram (mg/kg) body weight per day, respectively, for 40 days.
The researchers then collected blood and brain samples after 10, 20, 30, and 40 days from the beginning of the experiment for biochemical analysis. The results showed that the consumption of aspartame reduced the antioxidant activities of glutathione and superoxide dismutase, and elevated oxidative stress by increasing malondialdehyde levels. In addition, aspartame consumption greatly reduced the levels of the brain neurotransmitters serotonin, GABA, and dopamine and increased the level of acetylcholine and norepinephrine. The effect of aspartame is dose-dependent.
The researchers concluded that long-term aspartame consumption damages brain function by increasing oxidative stress in brain tissue and disrupting neurotransmitters.'
Read more: Aspartame may be making you dumb: Study finds that the artificial sweetener disrupts your neurotransmitters
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