'Of all the genetic engineers who have renounced the technology—Arpad Pusztai, Belinda Martineau, Thierry Vrain, John Fagan and Michael Antoniou, among others—because of its shortsighted approach and ability to produce unintended and potentially toxic consequences, Caius Rommens' story may be the most compelling.
Rommens was director of research at Simplot Plant Sciences from 2000 to 2013 where he led development of the company's genetically engineered Innate potato. But over time, Rommens started to have serious doubts about his work and worried about potential health risks from eating the GMO potatoes, which are now sold in 4,000 supermarkets in the U.S.
Rommens' concerns about the GMO potato led him to write a book, Pandora's Potatoes, which was recently published. The book is a case study on how a scientist's initial enthusiasm about genetic engineering turns to doubt and fear as he realizes the hazards the technology can create.
I recently interviewed Caius Rommens about his work developing the GMO potato and the misgivings he now has about it.
Caius Rommens: I left my position as team leader at Monsanto to start an independent biotech effort at Simplot. During the 12 years I worked there, I designed a genetically modified potato that I believed was resistant to bruise and late blight, and that could be used to produce French fries that were less colored and less carcinogenic than normal fries.
The main genetic engineering of the Simplot GMO potatoes as described in your book was silencing genes called RNAi. What are some of the possible negative consequences of silencing genes?
CR: Silencing is not gene-specific. Any gene with a similar structure to the silencing construct may be silenced as well. It is even possible that the silencing that takes place inside the GM potatoes affects the genes of animals eating these GM potatoes. I am most concerned about bees that don't eat GM potatoes but may use GM potato pollen to feed their larvae. Based on my assessment of the literature, it appears that the silencing constructs are active in pollen.
You say that silencing the PPO (polyphenol oxidase, a gene responsible for browning in potatoes) gene increases toxins that accumulate in the GMO potatoes. Why are these toxins produced and what effects could these toxins produce on human health?'
Read more: GMO Potato Creator Now Fears Its Impact on Human Health
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